Showing titles in Genetics

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

How could a relatively simple chemical code give rise to the complexity of a human being? How could our human genome have evolved? And how does it actually work? Your genome defines you at the most profound level. That same genome is present in every one of the approximately 100,000 billion cells that make you who you are as an individual member of the human species. An important ingredient of the genome, and its essential nature, is memory .

From bestselling author David Quammen, a fascinating scientific detective story about how a transmissible cancer first discovered in Tasmanian devils is connected to the discovery that cancer in humans can be treated as a chronic illness, not a fatal one—a radically new approach that promises...

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation, but also experience related conditions themselves.

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

 DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction. 

Are humans unwitting partners in evolution with psychedelic plants? Darwin’s Pharmacy shows they are by weaving the evolutionary theory of sexual selection and the study of rhetoric together with the science and literature of psychedelic drugs. Long suppressed as components of the human tool kit, psychedelic plants can be usefully modeled as “eloquence adjuncts” that intensify a crucial component of sexual selection in humans: discourse.

The authors of the New York Times bestseller Super Brain present a bold new understanding of our genes and how simple changes in lifestyle can boost genetic activity. The leap into "radical well-being" is a promise waiting to be fulfilled. "You are not simply the sum total of...

Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?

To make this groundbreaking audiobook, Dr. James Lyons-Weiler combed through the past fifty years of published research on autism, exploring subjects such as genetic variation, mechanisms of neurotoxicity of metals and pesticides, and the central and combined roles of each in causing autism.

The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?

A revelatory account of how power, politics, and greed have placed the unfulfilled promise of personalized medicine at the center of American medicine The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our...

For over a century, opening the black box of embryonic development was the holy grail of biology. Evo Devo--Evolutionary Developmental Biology--is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

A powerful treatise that demonstrates the existence of altruism in nature, with surprising implications for human society. Does altruism exist? Or is human nature entirely selfish? In this eloquent and accessible book, famed biologist David Sloan Wilson provides new answers to this age-old question based on the latest developments in evolutionary science.

When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments.

In The Genealogical Adam and Eve, S. Joshua Swamidass tests a scientific hypothesis: What if the traditional account is somehow true, with the origins of Adam and Eve taking place alongside evolution? Building on well-established but overlooked science, Swamidass explains how it's possible for Adam and Eve to be rightly identified as the ancestors of everyone. 

Cancer has always been with us. It killed our hominid ancestors, the mammals they evolved from and the dinosaurs that trampled the ground before that. Tumours grow in pets, livestock and wild animals. Even tiny jelly-like Hydra - creatures that are little more than a tube full of water - can get cancer. Paradoxically, many of us think of cancer as a contemporary killer, a disease of our own making caused by our modern lifestyles. 

We’re constantly seeking answers to these fundamental human questions, and now, science has the answers. The foods we enjoy, the people we love, the emotions we feel, and the beliefs we hold can all be traced back to our DNA, germs, and environment. This witty, colloquial book is popular science at its best, describing in everyday language how genetics, epigenetics, microbiology, and psychology work together to influence our personality and actions.