Agentic AI is rewriting the rules of work—and not in the way most organizations are talking about it. In this inaugural episode of The GuideLine, Stuart Brown (Stu) speaks with Microsoft Corporate Vice President Ulrich Homann (Uli) about why the agentic shift is bigger than a technology upgrade or even a change-management effort. At its core, Uli argues, it reshapes how decisions get made, how work gets done, and what an enterprise really is.

Stu and Uli map the foundations behind AI, share a three part framework for understanding agentic systems, and explain what Microsoft calls the “frontier firm.” Along the way, they dig into the practical realities that leaders can’t ignore: data sovereignty, the enterprise memory layer, and the line between automating tasks and building truly intelligent workflows. They wrap with a candid look at what’s next for organizations, and for a workforce stepping into a world where AI agents are part of the team.

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