Brainforest Café cover art

Brainforest Café

Brainforest Café

By: SpectreVision Radio
Listen for free

In the Brainforest Café, Dennis McKenna discusses a wide range of topics related to philosophy, plant medicines, psychedelics and consciousness in nature. Guests are invited from diverse fields such as anthropology, neuroscience, and spirituality to explore various aspects of the human experience. Some of the topics that are covered in the Brainforest Café include the history and the role of plant medicines in traditional healing practices and the potential benefits of psychedelic-assisted therapy for mental health. The Brainforest Café also explores the cultural, social, and political implications of psychedelic use. Dennis McKenna shares his own personal experiences with plant medicines, offering insights and reflections on his own journey of self-discovery and transformation. The Brainforest Café is a thought-provoking and engaging exploration of the intersection between science, spirituality, and culture, and offers a valuable perspective on the potential of plant medicines to transform our understanding of ourselves and the natural world. McKenna Academy of Natural Philosophyhttps://mckenna.academy/ SpectreVision Radio is a bespoke podcast network at the intersection between the arts and the uncanny, featuring a tapestry of shows exploring the anomalous, the luminous, and the numinous. We’re a community for creators and fans vibrating around common curiosities, shared interests and persistent passions. spectrevisionradio.com linktr.ee/spectrevision© 2026 McKenna Academy of Natural Philosophy Nature & Ecology Philosophy Science Social Sciences
Episodes
  • Can Plants Replace Animals in Drug Testing?

    Can Plants Replace Animals in Drug Testing?
    Jul 13 2026
    In this episode of the Brainforest Café, Dennis McKenna sits down with medicinal chemist Matt Metcalf to explore a genuinely strange frontier: testing drugs in pea seedlings and the touch-sensitive Mimosa pudica instead of in mice. Along the way they circle the question that started it all, why the opium poppy spends so much energy making opioids at all, and what those molecules might be doing inside a plant that has no nerves. - - - Matthew Metcalf is a neuroscientist with a background in the medicinal chemistry and pharmacology of opioids and cannabinoids as analgesic drugs. He is an assistant professor of Medicinal Chemistry at the Massachusetts College of Pharmacy and Health Sciences University (MCPHS) School of Pharmacy - Worcester. His current research focuses on the development of New Approach Methodologies (NAMs, sometimes called Non-Animal Models) drug tests to limit the use of animals used in drug testing. His current work focuses on the use of living plants as the biological organisms to replace animal models used as drug tests. Outside of his research he is passionate about auroras and timelapse photography. Learn more about your ad choices. Visit megaphone.fm/adchoices
    Show More Show Less
    1 hr and 9 mins
  • The Pharmacy Was Always the Pantry

    The Pharmacy Was Always the Pantry
    Jun 29 2026
    Dennis McKenna sits down with his old friend Dr. Cedric Baker, an ethnopharmacologist and medical herbalist who studies the ethnobotany of food across more than thirty countries. Together they take apart one of modern medicine's most stubborn assumptions: that food and medicine are separate things. From Thai kitchens where every dish is therapeutic, to the world's longevity hotspots, to the ethics of who owns a plant, it's a conversation that will leave you looking at your own plate a little differently. - - - Cedric Barrett Baker is an ethnopharmacologist, food ethnopharmacognoist, medicinal food ethnobotanist, integrative oncology medical herbalist, pharmaconutrition research scientist, & medical botany, pharmacognosy and pharmacy historian. He is also a licensed Rph. Learn more about your ad choices. Visit megaphone.fm/adchoices
    Show More Show Less
    1 hr and 2 mins
  • Can Yeast Save Endangered Psychedelics?

    Can Yeast Save Endangered Psychedelics?
    Jun 14 2026
    As the psychedelic renaissance surges, wild sources are collapsing under demand—peyote takes decades to grow, safrole extraction is destroying Southeast Asian forests, and Sonoran Desert toads are being overharvested. In his book Bioengineering Enlightenment, Prof. Jeffrey Gerst proposes a radical solution: engineer yeast or fast-growing plants to produce psychedelic compounds sustainably. But at what cost? Dennis McKenna warns this could strip these substances from their cultural and ecological roots, veering into biopiracy. Together, they debate biotech vs. tradition, exploring alternatives like community-led agroforestry, symbiotic rights, and the “Om Fund” to return profits to Indigenous stewards. They also revisit Terence McKenna’s “Stoned Ape” hypothesis, asking whether paleogenomics could experimentally probe the evolution of human consciousness. - - - Jeffrey Gerst, born and raised in New York, is a Professor of Biology with over three decades of academic experience. He began his career at the Mount Sinai School of Medicine and has since held a long-standing position at the Weizmann Institute of Science in Israel, where he serves as the Besen-Brender Chair of Microbiology and Parasitology. His research focuses on how proteins are correctly localized within cells, particularly through the trafficking of messenger RNA (mRNA), a process essential for normal cellular function and disease prevention. Among his key contributions, Gerst’s work has demonstrated that mammalian cells can transfer mRNA between one another, revealing a novel form of intercellular communication. His lab is now exploring this mechanism as a potential gene therapy approach to treat rare genetic disorders such as Tay-Sachs, cystic fibrosis, and Gaucher’s disease by enabling targeted RNA delivery within the body. In addition to his biomedical research, Gerst advocates for the sustainable production of psychedelic compounds using genetic engineering. He is the author of Bioengineering Enlightenment and has presented this work at major scientific conferences. Learn more about your ad choices. Visit megaphone.fm/adchoices
    Show More Show Less
    1 hr and 13 mins
adbl_web_anon_alc_button_suppression_t1
No reviews yet